Cheesecake is not alone in the list of baked goods that require refrigeration. Store cakes and other baked delicacies made with a cream cheese filling or frosting in the refrigerator. Chill custard and pumpkin pies made with perishable dairy ingredients such as eggs and milk.
How long can you leave cream cheese at room temperature?
That's because disease-causing bacteria like E.coli grow fastest between 40°F and 140°F. So according to the food safety experts at the US government, cream cheese shouldn't be out of the fridge for longer than two hours.
Do you have to refrigerate cake with whipped cream frosting?
The small amount of milk is stabilized by the large amount of sugar and considered safe at room temperature for two to three days. Always refrigerate any cake with a frosting that contains eggs or egg whites, or one that has whipped-cream frosting or any type of filling -- be it whipped cream, custard, fruit or mousse.